Mitotic perturbations induced by Nek2 overexpression require interaction with TRF1 in breast cancer cells
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منابع مشابه
Mitotic perturbations induced by Nek2 overexpression require interaction with TRF1 in breast cancer cells
NIMA-related kinase 2 (Nek2), a serine-threonine protein kinase, plays a major role in mitotic progression, including timing of mitotic entry, chromatin condensation, spindle organization, and cytokinesis. Nek2 overexpression results in premature centrosome separation, while kinase death Nek2 mutant expression or Nek2-depleted cells lead to centrosome separation failure. In addition, it has bee...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2013
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.26589